

In comparison to the patients who received chromium picolinate, those who received metformin had significantly lower levels of testosterone (p=0.001) and free testosterone (p=0.001) after 3 months of treatment.

In the same way, the serum levels of fasting insulin had significantly decreased leading to an increase in insulin sensitivity as measured by QUICKI index (p=0.014). Results: Chromium picolinate significantly decreased fasting blood sugar (FBS) after 3 months of treatment (p=0.042). Ovulation and pregnancy rate was measured in the two study groups, as well. Anthropometric and hormonal profile were measured and compared both before and after the treatment. The subjects were randomly assigned to two groups receiving either chromium picolinate (200µg daily) or metformin (1500mg daily) for 3 months.
#Chromium picolinate 1000 mcg and metformin trial
Materials and Methods: The present randomized clinical trial was performed on 92 women with clomiphen citrate-resistant PCOS at the clinics which were affiliated to Shiraz University of Medical Sciences, Shiraz, Iran.

metformin in clomiphen citrate resistant PCOS patients. Objective: To compare the effects of chromium picolinate vs. Background: Chromium picolinate could be effective in clomiphen citrate resistant PCOS patients.
